Endocrine Abstracts

Introduction: The main causes of death in the world today is non-communicable diseases (NCDs). A research of the World Bank found out that 82% of deaths in Ukraine are caused by chronic NCDs, 3.6% of which compose diabetes mellitus. And since the course of type 2 diabetes mellitus (T2DM) is usually long, it requires special, costly medical care for significant period of patient’s lifetime.Materials and results: Our research involved 592 males and 11...

Introduction and objectives: About 9% of world population suffer from acne, which occupies the 8th place among all human diseases, and the 3d place among dermatological disorders. Acne is diagnosed in 54% of 18 year aged women. Acne manifests mostly in 12–14 year age and regresses after 20 year age, even though more and more women have recently addressed their doctors for acne problem developing after 20 year age. Location of this dermatosis in open areas of skin leads to...

Introduction: About 80% of people had acne of some form. This dermatosis manifests at age 12–14, when there is a physiological increase in the level of hormones, and in most cases it regresses at 18–22. However today, the number of women with acne at age 25 and older has significantly increased.Methodology: Conducted was prospective observational study involving 126 women aged 19 to 37 years with inflammatory form of acne of different severity....

Among diseases with impaired carbohydrate metabolism, DM type 2 takes first place. And one of the main complications of this non-communicable disease is cardiovascular lesions. Our joint Ukraine-Poland research to actively detect DM type 2 took place during the Euro-2012, where we examined Hb1Ac in different ages of the population in both countries. In Ukraine the study involved 1564 individuals who where tested although they considered themselves free of DM. Their ages varied...

Aim: To investigate the clinical efficacy of the treatment of patients with neuro-ishemic diabetic foot ulcers (DF) by using sorption-antimicrobial nanocomposition based on silica sorbents.Methods: Hydrophobic-hydrophilic sorption-antibacterial nanocomposition, offered for the treatment of ulcers and wounds, contains sorbents (nano-disperse silicon dioxide, polymethylsiloxane) and antibacterial components (decamethoxin, metronidazole). In this study 78 p...

In patients with type 2 diabetes mellitus (T2DM), cardiovascular lesions are 3–4 times more often than in non-diabetics. Screening for T2DM in 1564 people from all Ukraine revealed that 12% had HbA1c at 6.1–6.4% and 16% had HbA1c above 6.5%. Those with HbA1c above 6.5% were examined for BMI, glycemia, total cholesterol, HDL-C, non-HDL-C. Dyslipidemia was defined as total cholesterol over 5.20 mmol/l, HDL-C – less than 1.02 mmol/l for males and less than 1.29 mmo...

Purpose: To improve methods of plastic closure of wound defects in patients with diabetic foot syndrome using skin flaps on vascular pedicle of the perforating vessels.Methods: The study involved patients with diabetes type 2 complicated with diabetic foot syndrome neuroischemic form. The study included 31 patients, 15 people in the study group and 16 people - the control group. Area wounds ranged from 3.8 to 21 cm2. Cleansing the wounds was p...

Introduction: Worldwide, patients with type 2 diabetes mellitus (T2DM) compose 90–95% of total number of diabetics. 10% of people aged under 60 years are affected with T2DM, also are 10–20% of people aged 60–69 years, and 15–20% over the age of 70 years. The risk of diabetes may reach 30–40% during lifetime due to other factors than age. T2DM is characterised by higher development of cardiovascular lesions, which even more worsens the condition of the ...

Diabetes mellitus type 2 (DM type 2) is characterized by constant increase in the number of cases. The worst consequence of this disease is the increase in mortality from injuries of the cardiovascular system. And the best prevention of this complication is active detection and then intensive treatment of DM type 2.Our study is aimed at active detection of patients with impaired glucose metabolism in different regions of Ukraine with help of determinatio...

Introduction: Diabetic foot is one of the leading disabling chronic complications of diabetes. From 40 to 60% (and in some regions up to 90%) of all non-traumatic amputations are performed in patients with diabetes. According to international epidemiological studies, the incidence of amputations reaches 206 cases per 100 thousand. In Ukraine in 2015, up to 2656 lower limb amputations were performed in patients with diabetes, which is 0.62 persons per 10 000 of population.<...